Clinical guidance update

Following a Medicine Supply Notification issued on 3 April 2024 about a national shortage and proposed discontinuation of parenteral (injectable) forms of Pabrinex, DHSC and NHSE have now developed additional clinical guidance for the treatment of alcohol dependence. Clinicians should consider prescribing the equivalent dose of unlicensed injectable thiamine where Pabrinex® is unavailable (which contains 250mg thiamine), where deemed clinically appropriate.